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Association of caffeine and related analytes with resistance to Parkinson disease among LRRK2 mutation carriers: A metabolomic study

OBJECTIVE: To identify markers of resistance to developing Parkinson disease (PD) among LRRK2 mutation carriers (LRRK2+), we carried out metabolomic profiling in individuals with PD and unaffected controls (UC), with and without the LRRK2 mutation. METHODS: Plasma from 368 patients with PD and UC in...

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Detalles Bibliográficos
Autores principales: Crotty, Grace F., Maciuca, Romeo, Macklin, Eric A., Wang, Junhua, Montalban, Manuel, Davis, Sonnet S., Alkabsh, Jamal I., Bakshi, Rachit, Chen, Xiqun, Ascherio, Alberto, Astarita, Giuseppe, Huntwork-Rodriguez, Sarah, Schwarzschild, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836665/
https://www.ncbi.nlm.nih.gov/pubmed/32999056
http://dx.doi.org/10.1212/WNL.0000000000010863