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The art of the possible in approaching efficacy trials for COVID19 convalescent plasma

COVID-19 convalescent plasma (CCP) is widely used as a treatment. Although there are sufficient safety data, high-level evidence of efficacy is still lacking. We summarize here the results from randomized controlled trials (RCTs) published to date and analyze their flaws and biases. We then provide...

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Detalles Bibliográficos
Autores principales: Focosi, Daniele, Farrugia, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836915/
https://www.ncbi.nlm.nih.gov/pubmed/33130197
http://dx.doi.org/10.1016/j.ijid.2020.10.074