Identification of the metabolites of ivermectin in humans

Mass drug administration of ivermectin has been proposed as a possible malaria elimination tool. Ivermectin exhibits a mosquito‐lethal effect well beyond its biological half‐life, suggesting the presence of active slowly eliminated metabolites. Human liver microsomes, primary human hepatocytes, and...

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Detalles Bibliográficos
Autores principales: Tipthara, Phornpimon, Kobylinski, Kevin C., Godejohann, Markus, Hanboonkunupakarn, Borimas, Roth, Alison, Adams, John H., White, Nicholas J., Jittamala, Podjanee, Day, Nicholas P. J., Tarning, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836931/
https://www.ncbi.nlm.nih.gov/pubmed/33497030
http://dx.doi.org/10.1002/prp2.712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836931/
https://www.ncbi.nlm.nih.gov/pubmed/33497030
http://dx.doi.org/10.1002/prp2.712

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