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Clinically relevant cell culture models and their significance in isolation, pathogenesis, vaccine development, repurposing and screening of new drugs for SARS-CoV-2: a systematic review

BACKGROUND: In-Vitro/Cellular evidence is the backbone and vital proof of concept during the development of novel therapeutics as well as drugs repurposing against COVID-19. Choosing an ideal in-vitro model is vital as the virus entry is through ACE2, CD147, and TMPRSS2 dependant and very specific....

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Detalles Bibliográficos
Autores principales: Kumar, Subodh, Sarma, Phulen, Kaur, Hardeep, Prajapat, Manisha, Bhattacharyya, Anusuya, Avti, Pramod, Sehkhar, Nishant, Kaur, Harpinder, Bansal, Seema, Mahendiratta, Saniya, Mahalmani, Vidya M., Singh, Harvinder, Prakash, Ajay, Kuhad, Anurag, Medhi, Bikash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836970/
https://www.ncbi.nlm.nih.gov/pubmed/33550034
http://dx.doi.org/10.1016/j.tice.2021.101497