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Polycations and polyanions in SARS-CoV-2 infection

We hypothesize that polycations, such as nuclear histones, released by neutrophils COVID-19 aggravate COVID-19 by multiple mechanisms: (A) Neutralization of the electrostatic repulsion between the virus particles and the cell membrane, thereby enhancing receptor-mediated entry. (B) Binding to the vi...

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Detalles Bibliográficos
Autores principales: Ginsburg, I., Fibach, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837050/
https://www.ncbi.nlm.nih.gov/pubmed/33412501
http://dx.doi.org/10.1016/j.mehy.2020.110470