PD-1 Blockade Aggravates Epstein–Barr Virus(+) Post-Transplant Lymphoproliferative Disorder in Humanized Mice Resulting in Central Nervous System Involvement and CD4(+) T Cell Dysregulations

Post-transplant lymphoproliferative disorder (PTLD) is one of the most common malignancies after solid organ or allogeneic stem cell transplantation. Most PTLD cases are B cell neoplasias carrying Epstein-Barr virus (EBV). A therapeutic approach is reduction of immunosuppression to allow T cells to...

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Detalles Bibliográficos
Autores principales: Volk, Valery, Theobald, Sebastian J., Danisch, Simon, Khailaie, Sahamoddin, Kalbarczyk, Maja, Schneider, Andreas, Bialek-Waldmann, Julia, Krönke, Nicole, Deng, Yun, Eiz-Vesper, Britta, Dragon, Anna Christina, von Kaisenberg, Constantin, Lienenklaus, Stefan, Bleich, Andre, Keck, James, Meyer-Hermann, Michael, Klawonn, Frank, Hammerschmidt, Wolfgang, Delecluse, Henri-Jacques, Münz, Christian, Feuerhake, Friedrich, Stripecke, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837057/
https://www.ncbi.nlm.nih.gov/pubmed/33511078
http://dx.doi.org/10.3389/fonc.2020.614876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837057/
https://www.ncbi.nlm.nih.gov/pubmed/33511078
http://dx.doi.org/10.3389/fonc.2020.614876

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