Cancer-Related Mutations Are Not Enriched in Naive Human Pluripotent Stem Cells

Previous analysis of RNA sequencing (RNA-seq) data from human naive pluripotent stem cells reported multiple point “mutations” in cancer-related genes and implicated selective culture conditions. We observed, however, that those mutations were only present in co-cultures with mouse feeder cells. Ins...

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Detalles Bibliográficos
Autores principales: Stirparo, Giuliano Giuseppe, Smith, Austin, Guo, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Matters Arising
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837212/
https://www.ncbi.nlm.nih.gov/pubmed/33321074
http://dx.doi.org/10.1016/j.stem.2020.11.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837212/
https://www.ncbi.nlm.nih.gov/pubmed/33321074
http://dx.doi.org/10.1016/j.stem.2020.11.014

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