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Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase
The superfamily 1 helicase nonstructural protein 13 (nsp13) is required for SARS-CoV-2 replication. The mechanism and regulation of nsp13 has not been explored at the single-molecule level. Specifically, force-dependent unwinding experiments have yet to be performed for any coronavirus helicase. Her...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837305/ https://www.ncbi.nlm.nih.gov/pubmed/33340543 http://dx.doi.org/10.1016/j.bpj.2020.11.2276 |
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