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Senescence Is Associated With Elevated Intracellular Resting [Ca(2 +)] in Mice Skeletal Muscle Fibers. An in vivo Study

Aging causes skeletal muscles to become atrophied, weak, and easily fatigued. Here, we have tested the hypothesis that normal aging in skeletal muscle cells is associated with Ca(2+) intracellular dyshomeostasis and oxidative stress. Intracellular Ca(2+) concentration ([Ca(2+)](i)), resting intracel...

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Detalles Bibliográficos
Autores principales: Mijares, Alfredo, Allen, Paul D., Lopez, Jose R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837333/
https://www.ncbi.nlm.nih.gov/pubmed/33510646
http://dx.doi.org/10.3389/fphys.2020.601189