The Influence of NAT2 Genotypes on Isoniazid Plasma Concentration of Pulmonary Tuberculosis Patients in Southern Thailand

BACKGROUND: Isoniazid (INH) is metabolized by polymorphic N-acetyltransferase 2 (NAT2) enzyme, which noticeably alters INH plasma concentration. We aimed to determine the distribution of NAT2 genotype in Thai tuberculosis (TB) patients and correlate their genotype with plasma INH concentrations. MET...

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Detalles Bibliográficos
Autores principales: Ungcharoen, Usanee, Sriplung, Hutcha, Mahasirimongkol, Surakameth, Chusri, Saranyou, Wichukchinda, Nuanjun, Mokmued, Phongpan, Wattanapokayakit, Sukanya, Chongsuvivatwong, Virasakdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Tuberculosis and Respiratory Diseases 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837378/
https://www.ncbi.nlm.nih.gov/pubmed/33138342
http://dx.doi.org/10.4046/trd.2020.0068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837378/
https://www.ncbi.nlm.nih.gov/pubmed/33138342
http://dx.doi.org/10.4046/trd.2020.0068

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