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The Influence of NAT2 Genotypes on Isoniazid Plasma Concentration of Pulmonary Tuberculosis Patients in Southern Thailand
BACKGROUND: Isoniazid (INH) is metabolized by polymorphic N-acetyltransferase 2 (NAT2) enzyme, which noticeably alters INH plasma concentration. We aimed to determine the distribution of NAT2 genotype in Thai tuberculosis (TB) patients and correlate their genotype with plasma INH concentrations. MET...
Autores principales: | Ungcharoen, Usanee, Sriplung, Hutcha, Mahasirimongkol, Surakameth, Chusri, Saranyou, Wichukchinda, Nuanjun, Mokmued, Phongpan, Wattanapokayakit, Sukanya, Chongsuvivatwong, Virasakdi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Tuberculosis and Respiratory Diseases
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837378/ https://www.ncbi.nlm.nih.gov/pubmed/33138342 http://dx.doi.org/10.4046/trd.2020.0068 |
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