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SNARE Zippering Is Suppressed by a Conformational Constraint that Is Removed by v-SNARE Splitting

Intracellular vesicle fusion is catalyzed by soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). Vesicle-anchored v-SNAREs pair with target membrane-associated t-SNAREs to form trans-SNARE complexes, releasing free energy to drive membrane fusion. However, trans-SNARE co...

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Detalles Bibliográficos
Autores principales: Liu, Yinghui, Wan, Chun, Rathore, Shailendra S., Stowell, Michael H.B., Yu, Haijia, Shen, Jingshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837384/
https://www.ncbi.nlm.nih.gov/pubmed/33440145
http://dx.doi.org/10.1016/j.celrep.2020.108611