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SNARE Zippering Is Suppressed by a Conformational Constraint that Is Removed by v-SNARE Splitting
Intracellular vesicle fusion is catalyzed by soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). Vesicle-anchored v-SNAREs pair with target membrane-associated t-SNAREs to form trans-SNARE complexes, releasing free energy to drive membrane fusion. However, trans-SNARE co...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837384/ https://www.ncbi.nlm.nih.gov/pubmed/33440145 http://dx.doi.org/10.1016/j.celrep.2020.108611 |