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Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis

Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides are the gold standard for insect control, they neg...

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Detalles Bibliográficos
Autores principales: Sterkel, Marcos, Haines, Lee R., Casas-Sánchez, Aitor, Owino Adung’a, Vincent, Vionette-Amaral, Raquel J., Quek, Shannon, Rose, Clair, Silva dos Santos, Mariana, García Escude, Natalia, Ismail, Hanafy M., Paine, Mark I., Barribeau, Seth M., Wagstaff, Simon, MacRae, James I., Masiga, Daniel, Yakob, Laith, Oliveira, Pedro L., Acosta-Serrano, Álvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837477/
https://www.ncbi.nlm.nih.gov/pubmed/33497373
http://dx.doi.org/10.1371/journal.pbio.3000796