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Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides are the gold standard for insect control, they neg...
Autores principales: | Sterkel, Marcos, Haines, Lee R., Casas-Sánchez, Aitor, Owino Adung’a, Vincent, Vionette-Amaral, Raquel J., Quek, Shannon, Rose, Clair, Silva dos Santos, Mariana, García Escude, Natalia, Ismail, Hanafy M., Paine, Mark I., Barribeau, Seth M., Wagstaff, Simon, MacRae, James I., Masiga, Daniel, Yakob, Laith, Oliveira, Pedro L., Acosta-Serrano, Álvaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837477/ https://www.ncbi.nlm.nih.gov/pubmed/33497373 http://dx.doi.org/10.1371/journal.pbio.3000796 |
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