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A protease protection assay for the detection of internalized alpha-synuclein pre-formed fibrils

Alpha-synuclein pre-formed fibrils (PFFs) represent a promising model system for the study of cellular processes underlying cell-to-cell transmission of alpha-synuclein proteopathic aggregates. However, the ability to differentiate the fate of internalized PFFs from those which remain in the extrace...

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Detalles Bibliográficos
Autores principales: Jarvela, Timothy S., Chaplot, Kriti, Lindberg, Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837481/
https://www.ncbi.nlm.nih.gov/pubmed/33497415
http://dx.doi.org/10.1371/journal.pone.0241161