Interaction of small molecules with the SARS-CoV-2 papain-like protease: In silico studies and in vitro validation of protease activity inhibition using an enzymatic inhibition assay

The SARS-CoV-2 virus is causing COVID-19, an ongoing pandemic, with extraordinary global health, social, and political implications. Currently, extensive research and development efforts are aimed at producing a safe and effective vaccine. In the interim, small molecules are being widely investigate...

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Detalles Bibliográficos
Autores principales: Pitsillou, Eleni, Liang, Julia, Ververis, Katherine, Hung, Andrew, Karagiannis, Tom C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837617/
https://www.ncbi.nlm.nih.gov/pubmed/33556646
http://dx.doi.org/10.1016/j.jmgm.2021.107851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837617/
https://www.ncbi.nlm.nih.gov/pubmed/33556646
http://dx.doi.org/10.1016/j.jmgm.2021.107851

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