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Data-driven reduction of dendritic morphologies with preserved dendro-somatic responses

Dendrites shape information flow in neurons. Yet, there is little consensus on the level of spatial complexity at which they operate. Through carefully chosen parameter fits, solvable in the least-squares sense, we obtain accurate reduced compartmental models at any level of complexity. We show that...

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Detalles Bibliográficos
Autores principales: Wybo, Willem AM, Jordan, Jakob, Ellenberger, Benjamin, Marti Mengual, Ulisses, Nevian, Thomas, Senn, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837682/
https://www.ncbi.nlm.nih.gov/pubmed/33494860
http://dx.doi.org/10.7554/eLife.60936