Endoplasmic Reticulum Stress Mediates Vascular Smooth Muscle Cell Calcification via Increased Release of Grp78 (Glucose-Regulated Protein, 78 kDa)-Loaded Extracellular Vesicles

Vascular calcification is common among aging populations and mediated by vascular smooth muscle cells (VSMCs). The endoplasmic reticulum (ER) is involved in protein folding and ER stress has been implicated in bone mineralization. The role of ER stress in VSMC-mediated calcification is less clear. A...

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Detalles Bibliográficos
Autores principales: Furmanik, Malgorzata, van Gorp, Rick, Whitehead, Meredith, Ahmad, Sadia, Bordoloi, Jayanta, Kapustin, Alexander, Schurgers, Leon J., Shanahan, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Translational Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837691/
https://www.ncbi.nlm.nih.gov/pubmed/33297752
http://dx.doi.org/10.1161/ATVBAHA.120.315506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837691/
https://www.ncbi.nlm.nih.gov/pubmed/33297752
http://dx.doi.org/10.1161/ATVBAHA.120.315506

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