Fibroblast Nox2 (NADPH Oxidase-2) Regulates ANG II (Angiotensin II)–Induced Vascular Remodeling and Hypertension via Paracrine Signaling to Vascular Smooth Muscle Cells

The superoxide-generating Nox2 (NADPH oxidase-2) is expressed in multiple cell types. Previous studies demonstrated distinct roles for cardiomyocyte, endothelial cell, and leukocyte cell Nox2 in ANG II (angiotensin II)–induced cardiovascular remodeling. However, the in vivo role of fibroblast Nox2 r...

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Detalles Bibliográficos
Autores principales: Harrison, Craig B., Trevelin, Silvia Cellone, Richards, Daniel A., Santos, Celio X.C., Sawyer, Greta, Markovinovic, Andrea, Zhang, Xiaohong, Zhang, Min, Brewer, Alison C., Yin, Xiaoke, Mayr, Manuel, Shah, Ajay M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837692/
https://www.ncbi.nlm.nih.gov/pubmed/33054395
http://dx.doi.org/10.1161/ATVBAHA.120.315322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837692/
https://www.ncbi.nlm.nih.gov/pubmed/33054395
http://dx.doi.org/10.1161/ATVBAHA.120.315322

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