Intraductal papillary mucinous neoplasm of the biliary tract with cardiac metastasis: A case report
INTRODUCTION: Intraductal papillary mucinous neoplasm of the biliary tract (IPNB) is a rare, low-grade neoplasm limited to the bile duct mucosa. The malignant transformation rate is low, and there have been limited reports of metastasis to other organs. Herein, we presented a rare case of a patient...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Lippincott Williams & Wilkins
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837973/ https://www.ncbi.nlm.nih.gov/pubmed/33546060 http://dx.doi.org/10.1097/MD.0000000000024310 |
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author | Lee, Joo Hyung Kim, Hyung Sun Park, Ji Hyun Park, Joon Seong |
author_facet | Lee, Joo Hyung Kim, Hyung Sun Park, Ji Hyun Park, Joon Seong |
author_sort | Lee, Joo Hyung |
collection | PubMed |
description | INTRODUCTION: Intraductal papillary mucinous neoplasm of the biliary tract (IPNB) is a rare, low-grade neoplasm limited to the bile duct mucosa. The malignant transformation rate is low, and there have been limited reports of metastasis to other organs. Herein, we presented a rare case of a patient who was diagnosed with IPNB concurrent with invasive adenocarcinoma after surgery and was diagnosed with cardiac metastasis 6 months later. PATIENT CONCERNS: A 61-year-old male patient presented with abdominal pain to a local clinic. He was diagnosed with intrahepatic cholangiocarcinoma with pancreatitis and transferred to our hospital. DIAGNOSIS: Diagnostic testing (magnetic resonance imaging, endoscopic retrograde cholangiopancreatography, positron emission tomography-computed tomography) revealed a papillary neoplasm and invasive adenocarcinoma with papillary neoplasm in the periampullary lesion. INTERVENTIONS: Pancreaticoduodenectomy, right hemihepatectomy, and left lateral sectionectomy of the liver were performed. After surgery, we planned gemcitabine-based adjuvant chemotherapy. OUTCOMES: Upon completion of the sixth gemcitabine chemotherapy cycle, a hyperechoic, oval-shaped mass (1.3 × 2.6 cm) was found on the outer wall of the right atrium. Resection of a cardiac tumor in the right atrium and patch repair were performed. CONCLUSION: To our knowledge, no other case of cardiac metastasis found during observation after surgery for an IPNB has been described. IPNBs are known to be less aggressive and to have a lower metastasis rate than intraductal papillary mucinous neoplasms; therefore, the number of case reports describing metastasis after surgery is relatively low. Our case suggests that close observation is necessary in patients diagnosed with an IPNB. |
format | Online Article Text |
id | pubmed-7837973 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-78379732021-01-27 Intraductal papillary mucinous neoplasm of the biliary tract with cardiac metastasis: A case report Lee, Joo Hyung Kim, Hyung Sun Park, Ji Hyun Park, Joon Seong Medicine (Baltimore) 7100 INTRODUCTION: Intraductal papillary mucinous neoplasm of the biliary tract (IPNB) is a rare, low-grade neoplasm limited to the bile duct mucosa. The malignant transformation rate is low, and there have been limited reports of metastasis to other organs. Herein, we presented a rare case of a patient who was diagnosed with IPNB concurrent with invasive adenocarcinoma after surgery and was diagnosed with cardiac metastasis 6 months later. PATIENT CONCERNS: A 61-year-old male patient presented with abdominal pain to a local clinic. He was diagnosed with intrahepatic cholangiocarcinoma with pancreatitis and transferred to our hospital. DIAGNOSIS: Diagnostic testing (magnetic resonance imaging, endoscopic retrograde cholangiopancreatography, positron emission tomography-computed tomography) revealed a papillary neoplasm and invasive adenocarcinoma with papillary neoplasm in the periampullary lesion. INTERVENTIONS: Pancreaticoduodenectomy, right hemihepatectomy, and left lateral sectionectomy of the liver were performed. After surgery, we planned gemcitabine-based adjuvant chemotherapy. OUTCOMES: Upon completion of the sixth gemcitabine chemotherapy cycle, a hyperechoic, oval-shaped mass (1.3 × 2.6 cm) was found on the outer wall of the right atrium. Resection of a cardiac tumor in the right atrium and patch repair were performed. CONCLUSION: To our knowledge, no other case of cardiac metastasis found during observation after surgery for an IPNB has been described. IPNBs are known to be less aggressive and to have a lower metastasis rate than intraductal papillary mucinous neoplasms; therefore, the number of case reports describing metastasis after surgery is relatively low. Our case suggests that close observation is necessary in patients diagnosed with an IPNB. Lippincott Williams & Wilkins 2021-01-22 /pmc/articles/PMC7837973/ /pubmed/33546060 http://dx.doi.org/10.1097/MD.0000000000024310 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 7100 Lee, Joo Hyung Kim, Hyung Sun Park, Ji Hyun Park, Joon Seong Intraductal papillary mucinous neoplasm of the biliary tract with cardiac metastasis: A case report |
title | Intraductal papillary mucinous neoplasm of the biliary tract with cardiac metastasis: A case report |
title_full | Intraductal papillary mucinous neoplasm of the biliary tract with cardiac metastasis: A case report |
title_fullStr | Intraductal papillary mucinous neoplasm of the biliary tract with cardiac metastasis: A case report |
title_full_unstemmed | Intraductal papillary mucinous neoplasm of the biliary tract with cardiac metastasis: A case report |
title_short | Intraductal papillary mucinous neoplasm of the biliary tract with cardiac metastasis: A case report |
title_sort | intraductal papillary mucinous neoplasm of the biliary tract with cardiac metastasis: a case report |
topic | 7100 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837973/ https://www.ncbi.nlm.nih.gov/pubmed/33546060 http://dx.doi.org/10.1097/MD.0000000000024310 |
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