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Scutellarin inhibits caspase-11 activation and pyroptosis in macrophages via regulating PKA signaling

Inflammatory caspase-11 senses and is activated by intracellular lipopolysaccharide (LPS) leading to pyroptosis that has critical role in defensing against bacterial infection, whereas its excess activation under pathogenic circumstances may cause various inflammatory diseases. However, there are fe...

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Detalles Bibliográficos
Autores principales: Ye, Jiezhou, Zeng, Bo, Zhong, Meiyan, Li, Hongchun, Xu, Lihui, Shu, Junxiang, Wang, Yaofeng, Yang, Fan, Zhong, Chunsu, Ye, Xunjia, He, Xianhui, Ouyang, Dongyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838020/
https://www.ncbi.nlm.nih.gov/pubmed/33532184
http://dx.doi.org/10.1016/j.apsb.2020.07.014