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Selective inhibition of CDK4/6: A safe and effective strategy for developing anticancer drugs
The sustained cell proliferation resulting from dysregulation of the cell cycle and activation of cyclin-dependent kinases (CDKs) is a hallmark of cancer. The inhibition of CDKs is a highly promising and attractive strategy for the development of anticancer drugs. In particular, third-generation CDK...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838032/ https://www.ncbi.nlm.nih.gov/pubmed/33532179 http://dx.doi.org/10.1016/j.apsb.2020.05.001 |