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Selective inhibition of CDK4/6: A safe and effective strategy for developing anticancer drugs

The sustained cell proliferation resulting from dysregulation of the cell cycle and activation of cyclin-dependent kinases (CDKs) is a hallmark of cancer. The inhibition of CDKs is a highly promising and attractive strategy for the development of anticancer drugs. In particular, third-generation CDK...

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Detalles Bibliográficos
Autores principales: Yuan, Kai, Wang, Xiao, Dong, Haojie, Min, Wenjian, Hao, Haiping, Yang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838032/
https://www.ncbi.nlm.nih.gov/pubmed/33532179
http://dx.doi.org/10.1016/j.apsb.2020.05.001