Chrysin serves as a novel inhibitor of DGKα/FAK interaction to suppress the malignancy of esophageal squamous cell carcinoma (ESCC)

Among current novel druggable targets, protein–protein interactions (PPIs) are of considerable and growing interest. Diacylglycerol kinase α (DGKα) interacts with focal adhesion kinase (FAK) band 4.1-ezrin-radixin-moesin (FERM) domain to induce the phosphorylation of FAK Tyr397 site and promotes the...

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Detalles Bibliográficos
Autores principales: Chen, Jie, Wang, Yan, Zhao, Di, Zhang, Lingyuan, Zhang, Weimin, Fan, Jiawen, Li, Jinting, Zhan, Qimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838054/
https://www.ncbi.nlm.nih.gov/pubmed/33532186
http://dx.doi.org/10.1016/j.apsb.2020.07.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838054/
https://www.ncbi.nlm.nih.gov/pubmed/33532186
http://dx.doi.org/10.1016/j.apsb.2020.07.011

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