Discovery of novel diarylamides as orally active diuretics targeting urea transporters

Urea transporters (UT) play a vital role in the mechanism of urine concentration and are recognized as novel targets for the development of salt-sparing diuretics. Thus, UT inhibitors are promising for development as novel diuretics. In the present study, a novel UT inhibitor with a diarylamide scaf...

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Detalles Bibliográficos
Autores principales: Zhang, Shun, Zhao, Yan, Wang, Shuyuan, Li, Min, Xu, Yue, Ran, Jianhua, Geng, Xiaoqiang, He, Jinzhao, Meng, Jia, Shao, Guangying, Zhou, Hong, Ge, Zemei, Chen, Guangping, Li, Runtao, Yang, Baoxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838058/
https://www.ncbi.nlm.nih.gov/pubmed/33532188
http://dx.doi.org/10.1016/j.apsb.2020.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838058/
https://www.ncbi.nlm.nih.gov/pubmed/33532188
http://dx.doi.org/10.1016/j.apsb.2020.06.001

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