Mechanism of action of a T cell-dependent bispecific antibody as a breakthrough immunotherapy against refractory colorectal cancer with an oncogenic mutation

T cell-dependent bispecific antibody (TDB)-induced T cell activation, which can eliminate tumor cells independent of MHC engagement, is expected to be a novel breakthrough immunotherapy against refractory cancer. However, the mechanism of action of TDBs has not been fully elucidated thus far. We foc...

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Detalles Bibliográficos
Autores principales: Kamakura, Daisuke, Asano, Ryutaro, Kawai, Hiroki, Yasunaga, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838078/
https://www.ncbi.nlm.nih.gov/pubmed/32666260
http://dx.doi.org/10.1007/s00262-020-02667-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838078/
https://www.ncbi.nlm.nih.gov/pubmed/32666260
http://dx.doi.org/10.1007/s00262-020-02667-9

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