Liraglutide, 7,8-DHF and their co-treatment prevents loss of vision and cognitive decline in a Wolfram syndrome rat model

Wolfram syndrome (WS) is a monogenic progressive neurodegenerative disease and is characterized by various neurological symptoms, such as optic nerve atrophy, loss of vision, cognitive decline, memory impairment, and learning difficulties. GLP1 receptor agonist liraglutide and BDNF mimetic 7,8-dihyd...

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Detalles Bibliográficos
Autores principales: Seppa, Kadri, Jagomäe, Toomas, Kukker, Kaia Grete, Reimets, Riin, Pastak, Marko, Vasar, Eero, Terasmaa, Anton, Plaas, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838169/
https://www.ncbi.nlm.nih.gov/pubmed/33500541
http://dx.doi.org/10.1038/s41598-021-81768-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838169/
https://www.ncbi.nlm.nih.gov/pubmed/33500541
http://dx.doi.org/10.1038/s41598-021-81768-6

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