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Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected

Statins lower the risk of cardiovascular events but have been associated with mitochondrial functional changes in a tissue-dependent manner. We investigated tissue-specific modifications of mitochondrial function in liver, heart and skeletal muscle mediated by chronic statin therapy in a Göttingen M...

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Detalles Bibliográficos
Autores principales: Christiansen, Liselotte Bruun, Dohlmann, Tine Lovsø, Ludvigsen, Trine Pagh, Parfieniuk, Ewa, Ciborowski, Michal, Szczerbinski, Lukasz, Kretowski, Adam, Desler, Claus, Tiano, Luca, Orlando, Patrick, Martinussen, Torben, Olsen, Lisbeth Høier, Larsen, Steen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838180/
https://www.ncbi.nlm.nih.gov/pubmed/33500513
http://dx.doi.org/10.1038/s41598-021-81846-9