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Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected
Statins lower the risk of cardiovascular events but have been associated with mitochondrial functional changes in a tissue-dependent manner. We investigated tissue-specific modifications of mitochondrial function in liver, heart and skeletal muscle mediated by chronic statin therapy in a Göttingen M...
Autores principales: | Christiansen, Liselotte Bruun, Dohlmann, Tine Lovsø, Ludvigsen, Trine Pagh, Parfieniuk, Ewa, Ciborowski, Michal, Szczerbinski, Lukasz, Kretowski, Adam, Desler, Claus, Tiano, Luca, Orlando, Patrick, Martinussen, Torben, Olsen, Lisbeth Høier, Larsen, Steen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838180/ https://www.ncbi.nlm.nih.gov/pubmed/33500513 http://dx.doi.org/10.1038/s41598-021-81846-9 |
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