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Measurement of hindered diffusion in complex geometries for high-speed studies of single-molecule forces

In a high-speed single-molecule experiment with a force probe, a protein is tethered between two substrates that are manipulated to exert force on the system. To avoid nonspecific interactions between the protein and nearby substrates, the protein is usually attached to the substrates through long,...

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Detalles Bibliográficos
Autores principales: Bartsch, Tobias F., Villasante, Camila M., Hengel, Felicitas E., Touré, Ahmed, Firester, Daniel M., Oswald, Aaron, Hudspeth, A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838191/
https://www.ncbi.nlm.nih.gov/pubmed/33500438
http://dx.doi.org/10.1038/s41598-021-81593-x