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Orthogonal translation enables heterologous ribosome engineering in E. coli

The ribosome represents a promising avenue for synthetic biology, but its complexity and essentiality have hindered significant engineering efforts. Heterologous ribosomes, comprising rRNAs and r-proteins derived from different microorganisms, may offer opportunities for novel translational function...

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Detalles Bibliográficos
Autores principales: Kolber, Natalie S., Fattal, Ranan, Bratulic, Sinisa, Carver, Gavriela D., Badran, Ahmed H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838251/
https://www.ncbi.nlm.nih.gov/pubmed/33500394
http://dx.doi.org/10.1038/s41467-020-20759-z