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TROAP switches DYRK1 activity to drive hepatocellular carcinoma progression

Hepatocellular carcinoma (HCC) is one of the common malignancy and lacks effective therapeutic targets. Here, we demonstrated that ectopic expression of trophinin-associated protein (TROAP) dramatically drove HCC cell growth assessed by foci formation in monolayer culture, colony formation in soft a...

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Detalles Bibliográficos
Autores principales: Li, Lei, Wei, Jia-Ru, Song, Ye, Fang, Shuo, Du, Yanyu, Li, Zhuo, Zeng, Ting-Ting, Zhu, Ying-Hui, Li, Yan, Guan, Xin-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838256/
https://www.ncbi.nlm.nih.gov/pubmed/33500384
http://dx.doi.org/10.1038/s41419-021-03422-3