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Onchocerca volvulus bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice

This study tests the hypothesis that an Onchocerca volvulus vaccine, consisting of two recombinant antigens (Ov-103 and Ov-RAL-2) formulated with the combination-adjuvant Advax-2, can induce protective immunity in genetically diverse Collaborative Cross recombinant inbred intercross mice (CC-RIX). C...

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Detalles Bibliográficos
Autores principales: Ryan, Nathan M., Hess, Jessica A., de Villena, Fernando Pardo-Manuel, Leiby, Benjamin E., Shimada, Ayako, Yu, Lei, Yarmahmoodi, Amir, Petrovsky, Nikolai, Zhan, Bin, Bottazzi, Maria Elena, Makepeace, Benjamin L., Lustigman, Sara, Abraham, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838260/
https://www.ncbi.nlm.nih.gov/pubmed/33500417
http://dx.doi.org/10.1038/s41541-020-00276-2