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Onchocerca volvulus bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice
This study tests the hypothesis that an Onchocerca volvulus vaccine, consisting of two recombinant antigens (Ov-103 and Ov-RAL-2) formulated with the combination-adjuvant Advax-2, can induce protective immunity in genetically diverse Collaborative Cross recombinant inbred intercross mice (CC-RIX). C...
Autores principales: | Ryan, Nathan M., Hess, Jessica A., de Villena, Fernando Pardo-Manuel, Leiby, Benjamin E., Shimada, Ayako, Yu, Lei, Yarmahmoodi, Amir, Petrovsky, Nikolai, Zhan, Bin, Bottazzi, Maria Elena, Makepeace, Benjamin L., Lustigman, Sara, Abraham, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838260/ https://www.ncbi.nlm.nih.gov/pubmed/33500417 http://dx.doi.org/10.1038/s41541-020-00276-2 |
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