Cargando…

The HSP-RTK-Akt axis mediates acquired resistance to Ganetespib in HER2-positive breast cancer

Breast cancer is the leading cause of cancer-related death in women worldwide. Human epidermal growth factor receptor 2 (HER2)-positive subtype comprises 20% of sporadic breast cancers and is an aggressive disease. While targeted therapies have greatly improved its management, primary and acquired r...

Descripción completa

Detalles Bibliográficos
Autores principales: Eyermann, Christopher E., Haley, John D., Alexandrova, Evguenia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838268/
https://www.ncbi.nlm.nih.gov/pubmed/33500390
http://dx.doi.org/10.1038/s41419-021-03414-3