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The HSP-RTK-Akt axis mediates acquired resistance to Ganetespib in HER2-positive breast cancer
Breast cancer is the leading cause of cancer-related death in women worldwide. Human epidermal growth factor receptor 2 (HER2)-positive subtype comprises 20% of sporadic breast cancers and is an aggressive disease. While targeted therapies have greatly improved its management, primary and acquired r...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838268/ https://www.ncbi.nlm.nih.gov/pubmed/33500390 http://dx.doi.org/10.1038/s41419-021-03414-3 |