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Cell type-specific changes in transcriptomic profiles of endothelial cells, iPSC-derived neurons and astrocytes cultured on microfluidic chips

In vitro neuronal models are essential for studying neurological physiology, disease mechanisms and potential treatments. Most in vitro models lack controlled vasculature, despite its necessity in brain physiology and disease. Organ-on-chip models offer microfluidic culture systems with dedicated mi...

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Detalles Bibliográficos
Autores principales: Middelkamp, H. H. T., Verboven, A. H. A., De Sá Vivas, A. G., Schoenmaker, C., Klein Gunnewiek, T. M., Passier, R., Albers, C. A., ‘t Hoen, P. A. C., Nadif Kasri, N., van der Meer, A. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838281/
https://www.ncbi.nlm.nih.gov/pubmed/33500551
http://dx.doi.org/10.1038/s41598-021-81933-x