Targeted Ptpn11 deletion in mice reveals the essential role of SHP2 in osteoblast differentiation and skeletal homeostasis

The maturation and function of osteoblasts (OBs) rely heavily on the reversible phosphorylation of signaling proteins. To date, most of the work in OBs has focused on phosphorylation by tyrosyl kinases, but little has been revealed about dephosphorylation by protein tyrosine phosphatases (PTPases)....

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Detalles Bibliográficos
Autores principales: Wang, Lijun, Yang, Huiliang, Huang, Jiahui, Pei, Shaopeng, Wang, Liyun, Feng, Jian Q., Jing, Dian, Zhao, Hu, Kronenberg, Henry M., Moore, Douglas C., Yang, Wentian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838289/
https://www.ncbi.nlm.nih.gov/pubmed/33500396
http://dx.doi.org/10.1038/s41413-020-00129-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838289/
https://www.ncbi.nlm.nih.gov/pubmed/33500396
http://dx.doi.org/10.1038/s41413-020-00129-7

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