The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks

The Bloom syndrome helicase BLM interacts with topoisomerase IIIα (TOP3A), RMI1 and RMI2 to form the BTR complex, which dissolves double Holliday junctions to produce non-crossover homologous recombination (HR) products. BLM also promotes DNA-end resection, restart of stalled replication forks, and...

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Detalles Bibliográficos
Autores principales: Shorrocks, Ann-Marie K., Jones, Samuel E., Tsukada, Kaima, Morrow, Carl A., Belblidia, Zoulikha, Shen, Johanna, Vendrell, Iolanda, Fischer, Roman, Kessler, Benedikt M., Blackford, Andrew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838300/
https://www.ncbi.nlm.nih.gov/pubmed/33500419
http://dx.doi.org/10.1038/s41467-020-20818-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838300/
https://www.ncbi.nlm.nih.gov/pubmed/33500419
http://dx.doi.org/10.1038/s41467-020-20818-5

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