Hemodynamic Effects of a Soluble Guanylate Cyclase Stimulator, Riociguat, and an Activator, Cinaciguat, During NO-Modulation in Healthy Pigs

Cardiovascular diseases are often characterized by dysfunctional endothelium. To compensate for the related lack of nitric oxide (NO), a class of soluble guanylate cyclase (sGC) stimulators and activators have been developed with the purpose of acting downstream of NO in the NO-sGC-cGMP cascade. The...

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Detalles Bibliográficos
Autores principales: Næsheim, Torvind, How, Ole-Jakob, Myrmel, Truls
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Experimental Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838342/
https://www.ncbi.nlm.nih.gov/pubmed/32662299
http://dx.doi.org/10.1177/1074248420940897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838342/
https://www.ncbi.nlm.nih.gov/pubmed/32662299
http://dx.doi.org/10.1177/1074248420940897

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