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Fluoxetine Promotes Hippocampal Oligodendrocyte Maturation and Delays Learning and Memory Decline in APP/PS1 Mice

Oligodendrogenesis dysfunction impairs memory consolidation in adult mice, and an oligodendrocyte abnormality is an important change occurring in Alzheimer's disease (AD). While fluoxetine (FLX) is known to delay memory decline in AD models, its effects on hippocampal oligodendrogenesis are unc...

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Detalles Bibliográficos
Autores principales: Chao, Feng-lei, Zhang, Yi, Zhang, Lei, Jiang, Lin, Zhou, Chun-ni, Tang, Jing, Liang, Xin, Fan, Jin-hua, Dou, Xiao-yun, Tang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838348/
https://www.ncbi.nlm.nih.gov/pubmed/33519426
http://dx.doi.org/10.3389/fnagi.2020.627362