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Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract

S100A4, a member of the S100 family of multifunctional calcium-binding proteins, participates in several physiological and pathological processes. In this study, we demonstrate that S100A4 expression is robustly induced in differentiating fiber cells of the ocular lens and that S100A4 ((−/−)) knocko...

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Detalles Bibliográficos
Autores principales: Maddala, Rupalatha, Gao, Junyuan, Mathias, Richard T., Lewis, Tylor R., Arshavsky, Vadim Y., Levine, Adriana, Backer, Jonathan M., Bresnick, Anne R., Rao, Ponugoti V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838418/
https://www.ncbi.nlm.nih.gov/pubmed/33500475
http://dx.doi.org/10.1038/s41598-021-81611-y