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Knockdown of Wip1 Enhances Sensitivity to Radiation in HeLa Cells Through Activation of p38 MAPK

The objectives of the study were to investigate the functional role and potential mechanism of wild-type p53-induced phosphatase (Wip1) in cervical cancer cell line HeLa cells, along with the effect of knockdown of Wip1 in combination with γ-irradiation on the HeLa cells. Expression of Wip1 was sile...

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Detalles Bibliográficos
Autores principales: Wang, Hong-yong, Liu, Zhong-shan, Qiu, Ling, Guo, Jie, Li, Yun-feng, Zhang, Jun, Wang, Tie-jun, Liu, Xiao-dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838432/
https://www.ncbi.nlm.nih.gov/pubmed/26351212
http://dx.doi.org/10.3727/096504015X14386062091479