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siRNA Suppression of NEDD9 Inhibits Proliferation and Enhances Apoptosis in Renal Cell Carcinoma

Renal cell carcinoma (RCC) is the most lethal of all genitourinary malignancies. NEDD9/HEF1/Cas-L is a member of the Cas protein family and is known as a biomarker in multiple cancer types. In this study, we demonstrate for the first time that NEDD9 was upregulated in RCC tissue and cell lines. Immu...

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Detalles Bibliográficos
Autores principales: Wang, Jue, Yang, Wen-juan, Sun, Chao, Luan, Yun, Cheng, Guang-hui, Li, Kai-lin, Kong, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838447/
https://www.ncbi.nlm.nih.gov/pubmed/26351211
http://dx.doi.org/10.3727/096504015X14386062091442