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CPEB4-Promoted Paclitaxel Resistance in Ovarian Cancer In Vitro Relies on Translational Regulation of CSAG2

Background: Drug resistance is a major obstacle in chemotherapy for ovarian cancer, wherein the up regulation of drug-resistant genes plays an important role. The cytoplasmic polyadenylation element binding protein 4 (CPEB4) is an RNA binding protein that controls mRNA cytoplasmic polyadenylation an...

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Detalles Bibliográficos
Autores principales: Zhang, Yaqing, Gan, Hongyun, Zhao, Fei, Ma, Xiaomei, Xie, Xiaofeng, Huang, Rui, Zhao, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838559/
https://www.ncbi.nlm.nih.gov/pubmed/33519462
http://dx.doi.org/10.3389/fphar.2020.600994