Induction of Multidrug Resistance of Acute Myeloid Leukemia Cells by Cocultured Stromal Cells via Upregulation of the PI3K/Akt Signaling Pathway

This study aimed to investigate the role of the PI3K/Akt signaling pathway in multidrug resistance of acute myeloid leukemia (AML) cells induced by cocultured stromal cells. Human AML cell lines HL-60 and U937 were adhesion cocultured with human bone marrow stromal cell line HS-5 cells. Such cocultu...

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Detalles Bibliográficos
Autores principales: Chen, Ping, Jin, Qing, Fu, Qiang, You, Peidong, Jiang, Xi, Yuan, Qin, Huang, Huifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838662/
https://www.ncbi.nlm.nih.gov/pubmed/27656831
http://dx.doi.org/10.3727/096504016X14634208143021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838662/
https://www.ncbi.nlm.nih.gov/pubmed/27656831
http://dx.doi.org/10.3727/096504016X14634208143021

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