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Knockdown of SPOCK1 Inhibits the Proliferation and Invasion in Colorectal Cancer Cells by Suppressing the PI3K/Akt Pathway

Sparc/osteonectin, cwcv, and kazal-like domains proteoglycan (testican) 1 (SPOCK1), known as testican-1, were found to be involved in the development and progression of tumors. However, in colorectal cancer (CRC), the expression pattern of SPOCK1 and its functional role remain poorly investigated. I...

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Detalles Bibliográficos
Autores principales: Zhao, Ping, Guan, Hai-Tao, Dai, Zhi-Jun, Ma, Yu-Guang, Liu, Xiao-Xu, Wang, Xi-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838686/
https://www.ncbi.nlm.nih.gov/pubmed/28281964
http://dx.doi.org/10.3727/096504016X14685034103554