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Secondary Structural Model of MALAT1 Becomes Unstructured in Chronic Myeloid Leukemia and Undergoes Structural Rearrangement in Cervical Cancer

Long noncoding RNAs (lncRNAs) influence cellular function through binding events that often depend on the lncRNA secondary structure. One such lncRNA, metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), is upregulated in many cancer types and has a myriad of protein- and miRNA-binding s...

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Detalles Bibliográficos
Autores principales: Wang, Matthew C., McCown, Phillip J., Schiefelbein, Grace E., Brown, Jessica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838788/
https://www.ncbi.nlm.nih.gov/pubmed/33450947
http://dx.doi.org/10.3390/ncrna7010006