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Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses

Multi‐omics datasets can provide molecular insights beyond the sum of individual omics. Various tools have been recently developed to integrate such datasets, but there are limited strategies to systematically extract mechanistic hypotheses from them. Here, we present COSMOS (Causal Oriented Search...

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Detalles Bibliográficos
Autores principales: Dugourd, Aurelien, Kuppe, Christoph, Sciacovelli, Marco, Gjerga, Enio, Gabor, Attila, Emdal, Kristina B., Vieira, Vitor, Bekker‐Jensen, Dorte B., Kranz, Jennifer, Bindels, Eric.M.J., Costa, Ana S.H., Sousa, Abel, Beltrao, Pedro, Rocha, Miguel, Olsen, Jesper V., Frezza, Christian, Kramann, Rafael, Saez‐Rodriguez, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838823/
https://www.ncbi.nlm.nih.gov/pubmed/33502086
http://dx.doi.org/10.15252/msb.20209730