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Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses
Multi‐omics datasets can provide molecular insights beyond the sum of individual omics. Various tools have been recently developed to integrate such datasets, but there are limited strategies to systematically extract mechanistic hypotheses from them. Here, we present COSMOS (Causal Oriented Search...
Autores principales: | Dugourd, Aurelien, Kuppe, Christoph, Sciacovelli, Marco, Gjerga, Enio, Gabor, Attila, Emdal, Kristina B., Vieira, Vitor, Bekker‐Jensen, Dorte B., Kranz, Jennifer, Bindels, Eric.M.J., Costa, Ana S.H., Sousa, Abel, Beltrao, Pedro, Rocha, Miguel, Olsen, Jesper V., Frezza, Christian, Kramann, Rafael, Saez‐Rodriguez, Julio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838823/ https://www.ncbi.nlm.nih.gov/pubmed/33502086 http://dx.doi.org/10.15252/msb.20209730 |
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