Interspecies Scaling of Antibody–Drug Conjugates (ADC) for the Prediction of Human Clearance

Allometric scaling is a useful tool for the extrapolation of pharmacokinetic parameters from animals to humans. The objective of this study was to predict human clearance of antibody–drug conjugates (ADC) allometrically from one to three animal species and compare the predicted human clearance with...

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Detalles Bibliográficos
Autor principal: Mahmood, Iftekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839014/
https://www.ncbi.nlm.nih.gov/pubmed/33430196
http://dx.doi.org/10.3390/antib10010001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839014/
https://www.ncbi.nlm.nih.gov/pubmed/33430196
http://dx.doi.org/10.3390/antib10010001

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